In terms of "respect for persons," which of the following is required for individuals with diminished autonomy?

The principle of "respect for persons" as outlined in the Belmont Report is fundamentally about recognizing and honoring the autonomy of individuals while also safeguarding those with diminished autonomy. Individuals who have diminished autonomy, such as minors or those with certain physical or mental disabilities, require special considerations in research settings.

Therefore, the correct answer emphasizes that these individuals are entitled to protection. This involves ensuring that their rights and welfare are prioritized, providing additional safeguards, and making sure that their involvement in research is ethically justified and that they are not exploited. By acknowledging their diminished autonomy, researchers can create appropriate frameworks that help protect these individuals while still allowing them the opportunity to participate in research where it is in their best interest.

This approach remains consistent with ethical research practices, which seek to balance respect for individual autonomy with the imperative to protect vulnerable populations.