What does "assent" mean in the context of research participation?

In the context of research participation, "assent" specifically refers to the agreement of a participant, typically a minor or someone who may not have the legal capacity to give full informed consent, to take part in a study. This concept recognizes that while full consent must be provided by a legal guardian or parent, the participant should still be involved in the decision-making process and should express a willingness to participate. This alignment with ethical principles emphasizes respect for persons, which is a core value articulated in the Belmont Report. By obtaining assent, researchers acknowledge the participant’s autonomy and right to participate voluntarily, even if they are not legally able to provide consent themselves.