Which of the following is required for IRB composition?

The requirement for IRB composition emphasizes the need for a diverse perspective in reviewing research proposals involving human subjects. Having at least one scientist and one non-scientist ensures that the committee can evaluate research from both technical and ethical viewpoints. The scientific members bring expertise in the research methodology and potential outcomes, while the non-scientist members contribute insights on societal and ethical implications, ensuring that human subjects' rights and welfare are adequately safeguarded.

The presence of both types of members promotes a balanced assessment of the proposed research, fostering an environment that values ethical considerations alongside scientific rigor. This diverse composition helps prevent bias and promotes ethical standards in research involving human subjects, aligning with the principles outlined in the Belmont Report regarding respect for persons, beneficence, and justice.

In contrast, the other options do not represent accurate requirements for IRB composition. For instance, requiring all members to belong to the same profession would limit the necessary diversity and perspective needed for ethical oversight. Similarly, mandating that all members must be affiliated with the institution would exclude valuable external perspectives that can enhance the review process, and a gender-specific requirement does not have relevance to the ethical oversight function an IRB serves. Hence, the requirement for at least one scientist and one non-scientist